THE kidney failure it means that the kidneys are no longer doing their job well enough: removing toxins from the blood and excess water (through urine), and helping to maintain the balance of chemicals (sodium, potassium and calcium) in the body.
The kidneys also produce hormones that help control blood pressure. blood pressureto produce Red blood cells and keep the strong bonesso that its dysfunction carries with it Health problemsspecify by the National Institutes of Health (NIH) of the United States.
This is when the dreaded acute kidney failure can develop rapidly, which it can be fatal and requires intensive treatment.
It is always worth clarifying that a correct medical diagnosis is needed and steps to be taken to make it reversible.
Symptoms of acute renal failure
Aside from the fact that acute renal failure sometimes causes no signs and is detected through laboratory tests, Mayo Clinic list some symptoms to keep in mind to be alert.
- Decreased volume of urine excreted (diuresis), although sometimes it remains stable
- Fluid retention, causing swelling in the legs, ankles or feet
- Shortness of breath
- tiredness and weakness
- Disorientation
- Nausea
- Irregular heart rhythm
- Chest pain or tightness
- Convulsions or coma in severe cases
Can coffee increase the risk of kidney dysfunction?
Although some researches have linked the drinking coffee with kidney damageothers have reported that caffeine and the development of chronic kidney disease are unrelated.
In this contradiction, a new study conducted by researchers of the University of Toronto, Canada and Padua, Italymay offer an explanation for the different conclusions.
The new study, published in JAMA network opennotes that the presence of a particular genetic variant can lead to coffee three times more likely to cause kidney dysfunction.
They claim it is the rate at which a person metabolizes caffeine.
About half of the participants had the rs762551 variant of the CYP1A2 genewhich caused them to metabolize caffeine slower. This group was determined to be at greatest risk for kidney damage.
The study assessed kidney health by monitoring three accepted markers of renal dysfunction: albuminuria, hyperfiltration and hypertension, disseminate Medical News Today.
speed of metabolism
The study lasted 16 years and involved 1,180 participants from 18 to 45 years old.
THE Dr. Sara Mahdavi was the lead author as a research scientist in the Department of Family and Community Medicine at the University of Toronto.
After identifying those with the problematic CYP1A2 variant, Mahdavi determined, “It was remarkable to see how amazing the effects of coffee were in the group that had this genetic variant, but no effect in those that didn’t.”
People who metabolized caffeine more slowly and who drank three or more cups of coffee a day They had 2.7 times more likely to develop kidney dysfunction.
They were also 2.8 times more likely to do so develop hypertension.
How much is a lot of caffeine?
Coffee is known to contain many substances that can have various effects on the body, both beneficial and harmful.
“This specifies that caffeine from any source can be harmful in those people who have this genetic variant that affects their ability to clear caffeine from their system,” says the doctor.
Experts hope the results push for a new review of the current guidelines they approve up to 400 milligrams or four to five cupsof brewed coffee per day.
It’s worth noting, they point out, that decaffeinated coffee is virtually caffeine-free, so it wouldn’t generate an increased risk regardless of genetic factors.
Source: Clarin
Mary Ortiz is a seasoned journalist with a passion for world events. As a writer for News Rebeat, she brings a fresh perspective to the latest global happenings and provides in-depth coverage that offers a deeper understanding of the world around us.